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Jeffrey M. Friedman

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It’s all about your frame of mind

We think of brains as computers—stimulus in, action out. But they’re far more finicky than any iMac. Easily swayed by underlying internal states such as hunger, aggression, or arousal, our neurons are capable of incredible flexibility. For neuroscientists, it’s yet another wrinkle in understanding our wrinkliest organ.

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The radiogenetic remote control

Scientists studying appetite have developed new technology that makes mice hungry with the flip of a switch. What else could they do with it?